The bank is closing 140 branches across the country.
The Ramsbottom branch will close in June.
More than 12-hundred jobs are at risk - but the bank says it hopes to offer new roles to around a third of those affected.
The Spanish-owned company says it's making changes because more banking is done online and via apps.
In the last few years Ramsbottom has lost it's branches of Natwest and RBS.
WATCH: D-Day For Bury FC
Owner Steve Dale has until midnight to give the EFL guarantees that he can fund the club or they will be thrown out of the football league.
Steve Dale in talks with buyer for Bury
He's told Tower FM they are in discussions, but need more time
Parkinson Resigns
Phil Parkinson has handed in his resignation as manager of Bolton Wanderers.
