Officers were called to reports that a number of shots had been fired close to the Outline Health & Fitness Centre on Lever Street.
A man, who is believed to be in his late 20s, has been taken to hospital and the extent of his injuries isn't yet known.
There is a scene in place in Lever Street as police continue with their enquiries.
Superintendent Rick Jackson, from GMP’s Bolton District, said: “We believe this was a targeted shooting and we have no reason to believe there is a wider risk to the public.
“There is a large police presence at the scene as we continue with our enquiries and we are appealing for anyone who saw what happened, or witnessed anything suspicious, to get in touch.”
Anyone with information should call police on 0161 856 5599 quoting reference 1217 of 12/07/19 or the independent charity Crimestoppers, anonymously, on 0800 555 111.